Opportunities and challenges with microphysiological systems: a pharma end-user perspective
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/d41573-020-00030-2.pdf
Reference4 articles.
1. Jang, K. J. et al. Reproducing human and cross-species drug toxicities using a Liver-Chip. Sci. Transl Med. 11, eaax5516 (2019).
2. Franzen, N. et al. Impact of organ-on-a-chip technology on pharmaceutical R&D costs. Drug Discov. Today 24, 1720–1724 (2019).
3. Ewart, L. et al. Navigating tissue chips from development to dissemination: a pharmaceutical industry perspective. Exp. Biol. Med. 242, 1579–1585 (2017).
4. Clevers, H. Modeling development and disease with organoids. Cell 165, 1586–1597 (2016).
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