Organ-on-a-chip Technology Roadmap: Regulatory Framework, Industry Adoption, Key Players, Technology Transfer, Validation, and Ethical Considerations

Abstract

Advancement in organ-on-a-chip technology has caused increasing interest among pharmaceutical companies due to its potential to disrupt drug discovery and toxicology studies and reduce costs and animal tests. However, several challenges need to be addressed to make the technology widely adopted. Regulatory agencies need to validate the technology and conduct validation tests; standards need to be put in place to allow validation and data sharing; and techniques and materials for mass production and commercialization need to be developed. The chapter will start with a general overview of the factors surrounding technology adoption, and it will proceed to delve into the various arguments in more detail and from different perspectives.