Regulation of lipid binding underlies the activation mechanism of class IA PI3-kinases
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2011532.pdf
Reference51 articles.
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3. Bayascas JR . (2010). PDK1: the major transducer of PI 3-kinase actions. Curr Top Microbiol Immunol 346: 9–29.
4. Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI et al. (2010). The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nat Chem Biol 6: 117–124.
5. Burke JE, Vadas O, Berndt A, Finnegan T, Perisic O, Williams RL . (2011). Dynamics of the phosphoinositide 3-kinase p110δ interaction with p85α and membranes reveals aspects of regulation distinct from p110α. Structure 19: 1127–1137.
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