Genetic variation in the obesity gene FTO is not associated with decreased fat oxidation: the NEO study

Author:

Blauw L L,Noordam R,Trompet S,Berbée J F P,Rosendaal F R,van Heemst D,van Dijk K W,Mook-Kanamori D O,de Mutsert R,Rensen P C N

Publisher

Springer Science and Business Media LLC

Subject

Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism,Medicine (miscellaneous)

Reference45 articles.

1. American College of Cardiology/American Heart Association Task Force on Practice Guidelines, Obesity Expert Panel.. Executive summary: Guidelines (2013) for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Obesity Society published by the Obesity Society and American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Based on a systematic review from the The Obesity Expert Panel, 2013. Obesity (Silver Spring, MD) 2013; 22 (Suppl 2): S5–S39.

2. Loos RJ, Yeo GS . The bigger picture of FTO: the first GWAS-identified obesity gene. Nat Rev Endocrinol 2014; 10: 51–61.

3. Elks CE, den Hoed M, Zhao JH, Sharp SJ, Wareham NJ, Loos RJ et al. Variability in the heritability of body mass index: a systematic review and meta-regression. Front Endocrinol 2012; 3: 29.

4. Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (New York, NY) 2007; 316: 889–894.

5. Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 2007; 3: e115.

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