On the mode of action of mirabegron
Author:
Publisher
Springer Science and Business Media LLC
Subject
Urology
Link
http://www.nature.com/articles/nrurol.2015.297.pdf
Reference10 articles.
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3. D'Agostino, G., Condino, A. M., Calvi, P. Involvement of β3-adrenoceptors in the inhibitory control 3 of cholinergic activity in human bladder: direct evidence by [3H]-acetylcholine release experiments in the isolated detrusor. Eur. J. Pharmacol. 758, 115–122 (2015).
4. Alexandre, E. C. et al. Mirabegron relaxes urethral smooth muscle by a dual mechanism involving β3-adrenoceptor activation and α1-adrenoceptor blockade. Br. J. Pharmacol. http://dx.doi.org/10.1111/bph.13367 (2015).
5. Taki, N., Taniguchi, T., Okada, K., Moriyama, N. & Muramatsu, I. Evidence for predominant mediation of α1-adrenoceptor in the tonus of entire urethra of women. J. Urol. 162, 1829–1832 (1999).
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