Prime editing for precise and highly versatile genome manipulation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
https://www.nature.com/articles/s41576-022-00541-1.pdf
Reference148 articles.
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4. Jinek, M. et al. A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816 (2012). This paper reports the use of SpCas9 nuclease and nickases and the development of single-guide RNAs for programmable DNA cutting.
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