The role of Notch in tumorigenesis: oncogene or tumour suppressor?
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Earth and Planetary Sciences,General Environmental Science
Link
http://www.nature.com/articles/nrc1186.pdf
Reference138 articles.
1. Morgan, T. H. The theory of the gene. Am. Nat. 51, 513–544 (1917).
2. Wharton, K. A. et al. Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell 43, 567–581 (1985).
3. Kidd, S., Kelley, M. R. & Young, M. W. Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors. Mol. Cell Biol. 6, 3094–3108 (1986). References 2 and 3 are classic papers that describe the cloning of the Drosophila Notch gene.
4. Blaumueller, C. M. et al. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell 90, 281–291 (1997).
5. Logeat, F. et al. The Notch1 receptor is cleaved constitutively by a furin-like convertase. Proc. Natl Acad. Sci. USA 95, 8108–8112 (1998).
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