Structural diversity of anti-pancreatic cancer capsimycins identified in mangrove-derived Streptomyces xiamenensis 318 and post-modification via a novel cytochrome P450 monooxygenase-Reference-Cited by-同舟云学术

Structural diversity of anti-pancreatic cancer capsimycins identified in mangrove-derived Streptomyces xiamenensis 318 and post-modification via a novel cytochrome P450 monooxygenase

Published:2017-01-18 Issue:1 Volume:7 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Yu He-Lin,Jiang Shu-Heng,Bu Xu-Liang,Wang Jia-Hua,Weng Jing-Yi,Yang Xiao-Mei,He Kun-Yan,Zhang Zhi-Gang,Ao Ping,Xu Jun,Xu Min-Juan

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep40689.pdf

Reference35 articles.

1. Xu, D.-B., Ye, W.-W., Han, Y., Deng, Z.-X. & Hong, K. Natural products from mangrove actinomycetes. Mar Drugs 12, 2590–2613 (2014).

2. Xu, M.-J. et al. Deciphering the streamlined genome of Streptomyces xiamenensis 318 as the producer of the anti-fibrotic drug candidate xiamenmycin. Sci Rep 6, 18977 (2016).

3. Weber, T. et al. antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters. Nucleic Acids Res 43, W237–243 (2015).

4. Zhang, G. et al. Mechanistic insights into polycycle formation by reductive cyclization in ikarugamycin biosynthesis. Angewandte Chemie 53, 4840–4844 (2014).

5. Antosch, J., Schaefers, F. & Gulder, T. A. Heterologous reconstitution of ikarugamycin biosynthesis in E. coli. Angewandte Chemie 53, 3011–3014 (2014).

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