Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider-Reference-Cited by-同舟云学术

Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider

Published:2023-11-22 Issue:1 Volume:10 Page:
ISSN:2052-4463
Container-title:Scientific Data
language:en
Short-container-title:Sci Data

Author:

Korolkova Yuliya^ORCID,Mikov Alexander,Lobas Anna,Solovyeva Elizaveta,Surin Alexey,Andreev Yaroslav,Gorshkov Mikhail,Kozlov Sergey

Abstract

AbstractThe Tibellus oblongus spider is an active hunter that does not spin webs and remains highly underinvestigated in terms of the venom composition. Here, we describe venom glands transcriptome and venom proteome analysis for unveiling the polypeptide composition of Tibellus oblongus spider venom. The resulting EST database includes 1733 records, including 1263 nucleotide sequences with ORFs, of these 942 have been identified as toxin-coding. The database of peptide sequences was built based on of the transcriptomics results. It contains 217 new toxins, 212 of them were detected in the T. oblongus venom by the proteomics.

Funder

Russian Science Foundation

Publisher

Springer Science and Business Media LLC

Subject

Library and Information Sciences,Statistics, Probability and Uncertainty,Computer Science Applications,Education,Information Systems,Statistics and Probability

Link

https://www.nature.com/articles/s41597-023-02703-0.pdf

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