Targeting Translation Control with p70 S6 Kinase 1 Inhibitors to Reverse Phenotypes in Fragile X Syndrome Mice
Author:
Publisher
Springer Science and Business Media LLC
Subject
Psychiatry and Mental health,Pharmacology
Link
http://www.nature.com/articles/npp2015369.pdf
Reference33 articles.
1. American Psychiatric Association (2013) Diagnostic and Statistical Manual of Mental Disorders, 5th edn. Americal Psychiatric Publishing: Arlington, VA.
2. Bhattacharya A, Kaphzan H, Alvarez-Dieppa AC, Murphy JP, Pierre P, Klann E (2012). Genetic removal of p70 S6 kinase 1 corrects molecular, synaptic, and behavioral phenotypes in fragile X syndrome mice. Neuron 76: 325–337.
3. Bowling H, Bhattacharya A, Zhang G, Lebowitz JZ, Alam D, Smith P et al (2016). BONLAC: a combinatorial proteomic technique to measure stimulus-induced translational profiles in brain slices. Neuropharmacology 100: 76–89.
4. Costa-Mattioli M, Sossin WS, Klann E, Sonenberg N (2009). Translational control of long-lasting synaptic plasticity and memory. Neuron 61: 10–26.
5. Couty S, Westwood IM, Kalusa A, Cano C, Travers J, Boxall K et al (2013). The discovery of potent ribosomal S6 kinase inhibitors by high-throughput screening and structure-guided drug design. Oncotarget 4: 1647–1661.
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