Promise of mGluR2/3 activators in psychiatry
Author:
Publisher
Springer Science and Business Media LLC
Subject
Psychiatry and Mental health,Pharmacology
Link
http://www.nature.com/articles/npp2008156.pdf
Reference6 articles.
1. Galici R, Echemendia NG, Rodriguez AL, Conn PJ (2005). A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity. J Pharmacol Exp Ther 315: 1181–1187.
2. Galici R, Jones CK, Hemstapat K, Nong Y, Echemendia NG, Williams LC et al (2006). Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice. J Pharmacol Exp Ther 318: 173–185.
3. Johnson MP, Baez M, Jagdmann Jr GE, Britton TC, Large TH, Callagaro DO et al (2003). Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2- trifluoroethylsulfonyl)pyrid-3-ylmethylamine. J Med Chem 46: 3189–3192.
4. Patil ST, Zhang L, Martenyi F, Lowe SL, Jackson KA, Andreev BV et al (2007). Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat Med 13: 1102–1107.
5. Schoepp DD, Marek GJ (2002). Preclinical pharmacology of mGlu2/3 receptor agonists: novel agents for schizophrenia? Curr Drug Target CNS Neurol Disord 1: 215–225.
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