Heat-inducible TNF-α gene therapy combined with hyperthermia using magnetic nanoparticles as a novel tumor-targeted therapy

Author:

Ito Akira,Shinkai Masashige,Honda Hiroyuki,Kobayashi Takeshi

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Reference26 articles.

1. Gerner EW, Hersh EM, Pennington M, et al . Heat-inducible vectors for use in gene therapy Int J Hyperthermia 2000 16: 171–181

2. Walther W, Stein U, Fichtner I, et al . mdr1 promoter-driven tumor necrosis factor-α expression for a chemotherapy-controllable combined in vivo gene therapy and chemotherapy of tumors Cancer Gene Ther 2000 7: 893–900

3. Manome Y, Kunieda T, Wen PK, et al . Transgene expression in malignant glioma using a replication-defective adenoviral vector containing the EGR-1 promoter: activation by ionizing radiation or uptake of radioactive iododeoxyuridine Hum Gene Ther 1998 9: 1409–1417

4. Bellomo G, Perotti M, Taddei F, et al . Tumor necrosis factor α induces apoptosis in mammary adenocarcinoma cells by an increase in intranuclear free Ca2+ concentration and DNA fragmentation Cancer Res 1992 52: 1342–1346

5. Palladino MA, Shalaby MR, Kramer SM, et al . Characterization of the antitumor activities of human tumor necrosis factor-α and the comparison with other cytokines: induction of tumor specific immunity J Immunol 1987 138: 4023–4032

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