Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/7700440.pdf
Reference47 articles.
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2. Culver KW, Ram Z, Wallbridge S et al. In vivo gene transfer with retroviral vector–producer cells for treatment of experimental brain tumors Science 1992 256: 1550–1552
3. Kucharczuk JC, Raper S, Elshami AA et al. Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in nonhuman primates Hum Gene Ther 1996 7: 2225–2233
4. Oldfield EH, Ram Z, Culver KW et al. Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir Hum Gene Ther 1993 4: 39–69
5. Ram Z, Culver KW, Oshiro EM et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells Nat Med 1997 3: 1354–1361
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