Epigenetic inheritance of acquired traits through sperm RNAs and sperm RNA modifications
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg.2016.106.pdf
Reference140 articles.
1. Landman, O. E. The inheritance of acquired characteristics. Annu. Rev. Genet. 25, 1–20 (1991).
2. Rechavi, O. et al. Starvation-induced transgenerational inheritance of small RNAs in C. elegans. Cell 158, 277–287 (2014).
3. Ost, A. et al. Paternal diet defines offspring chromatin state and intergenerational obesity. Cell 159, 1352–1364 (2014).
4. Ng, S. F. et al. Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring. Nature 467, 963–966 (2010).
5. Carone, B. R. et al. Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell 143, 1084–1096 (2010). References 4 and 5 show that acquired metabolic disorders due to paternal diets could be inherited by the offspring.
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