Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

Author:

Baryshnikova Anastasia,Costanzo Michael,Kim Yungil,Ding Huiming,Koh Judice,Toufighi Kiana,Youn Ji-Young,Ou Jiongwen,San Luis Bryan-Joseph,Bandyopadhyay Sunayan,Hibbs Matthew,Hess David,Gingras Anne-Claude,Bader Gary D,Troyanskaya Olga G,Brown Grant W,Andrews Brenda,Boone Charles,Myers Chad L

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Biochemistry,Biotechnology

Reference40 articles.

1. Baryshnikova, A. et al. Synthetic genetic array (SGA) analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe . Methods Enzymol. 470, 146–180 (2010).

2. Dixon, S.J., Costanzo, M., Baryshnikova, A., Andrews, B. & Boone, C. Systematic mapping of genetic interaction networks. Annu. Rev. Genet. 470, 145–179 (2009).

3. Collins, S.R., Schuldiner, M., Krogan, N.J. & Weissman, J.S. A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biol. 7, R63 (2006).

4. Breslow, D.K. et al. A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat. Methods 5, 711–718 (2008).

5. St Onge, R.P. et al. Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions. Nat. Genet. 39, 199–206 (2007).

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