Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling-Reference-Cited by-同舟云学术

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling

Published:2017-07-31 Issue:9 Volume:24 Page:743-751
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Ve Thomas^ORCID,Vajjhala Parimala R,Hedger Andrew,Croll Tristan,DiMaio Frank,Horsefield Shane,Yu Xiong,Lavrencic Peter,Hassan Zahid^ORCID,Morgan Garry P,Mansell Ashley,Mobli Mehdi^ORCID,O'Carroll Ailis,Chauvin Brieuc,Gambin Yann,Sierecki Emma,Landsberg Michael J,Stacey Katryn J,Egelman Edward H^ORCID,Kobe Bostjan^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/nsmb.3444.pdf

Reference76 articles.

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3. Gay, N.J., Symmons, M.F., Gangloff, M. & Bryant, C.E. Assembly and localization of Toll-like receptor signalling complexes. Nat. Rev. Immunol. 14, 546–558 (2014).

4. Hennessy, E.J., Parker, A.E. & O'Neill, L.A. Targeting Toll-like receptors: emerging therapeutics? Nat. Rev. Drug Discov. 9, 293–307 (2010).

5. Lin, S.C., Lo, Y.C. & Wu, H. Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling. Nature 465, 885–890 (2010).

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