Establishment of a novel cell-based assay for screening small molecule antagonists of human interleukin-6 receptor-Reference-Cited by-同舟云学术

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Establishment of a novel cell-based assay for screening small molecule antagonists of human interleukin-6 receptor

Published:2014-10-27 Issue:11 Volume:35 Page:1453-1462
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

He Yang-yang,Yan Yu,Zhang Chang,Li Peng-yuan,Wu Ping,Du Peng,Zeng Da-di,Fang Jian-song,Wang Shuang,Du Guan-hua

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/aps201490.pdf

Reference37 articles.

1. Hirano T . Interleukin 6 (IL-6) and its receptor: their role in plasma cell neoplasias. Int J Cell Cloning 1991; 9: 166–84.

2. Mi XB, Zeng FQ . Hypomethylation of interleukin-4 and -6 promoters in T cells from systemic lupus erythematosus patients. Acta Pharmacol Sin 2008; 29: 105–12.

3. Pelliniemi TT, Irjala K, Mattila K, Pulkki K, Rajamaki A, Tienhaara A, et al. Immunoreactive interleukin-6 and acute phase proteins as prognostic factors in multiple myeloma. Finnish Leukemia Group. Blood 1995; 85: 765–71.

4. Kishimoto T . The biology of interleukin-6. Blood 1989; 74: 1–10.

5. Wei ZF, Jiao XL, Wang T, Lu Q, Xia YF, Wang ZT, et al. Norisoboldine alleviates joint destruction in rats with adjuvant-induced arthritis by reducing RANKL, IL-6, PGE2, and MMP-13 expression. Acta Pharmacol Sin 2013; 34: 403–13.

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