SPECT imaging of interleukin-6 receptor in ovarian tumor xenografts with a novel radiotracer of 99mTc-HYNIC-Aca-LSLITRL-Reference-Cited by-同舟云学术

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SPECT imaging of interleukin-6 receptor in ovarian tumor xenografts with a novel radiotracer of 99mTc-HYNIC-Aca-LSLITRL

Published:2015-08-09 Issue:1 Volume:48 Page:91-101
ISSN:0939-4451
Container-title:Amino Acids
language:en
Short-container-title:Amino Acids

Author:

Li Fei,Zhang Zhenzhong,Cheng Teng,Wei Rui,Dai Yun,Lv Mengqin,Luo Danfeng,Zhu Xiaohua,Ma Ding,Xi Ling,Dong Qingjian,Ma Xiangyi

Funder

the National Nature and Science Foundations of China

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Clinical Biochemistry,Biochemistry

Link

http://link.springer.com/content/pdf/10.1007/s00726-015-2060-8.pdf

Reference35 articles.

1. Ananias HJ, Yu Z, Dierckx RA, van der Wiele C, Helfrich W, Wang F, Yan Y, Chen X, de Jong IJ, Elsinga PH (2011) (99m)technetium-HYNIC(tricine/TPPTS)-Aca-bombesin(7-14) as a targeted imaging agent with microSPECT in a PC-3 prostate cancer xenograft model. Mol Pharm 8(4):1165–1173. doi: 10.1021/mp200014h

2. Ataie-Kachoie P, Morris DL, Pourgholami MH (2013) Minocycline suppresses interleukin-6, its receptor system and signaling pathways and impairs migration, invasion and adhesion capacity of ovarian cancer cells: in vitro and in vivo studies. Plos One 8(4):e60817. doi: 10.1371/journal.pone.0060817

3. Cohen S, Bruchim I, Graiver D, Evron Z, Oron-Karni V, Pasmanik-Chor M, Eitan R, Bernheim J, Levavi H, Fishman A, Flescher E (2013) Platinum-resistance in ovarian cancer cells is mediated by IL-6 secretion via the increased expression of its target cIAP-2. J Mol Med 91(3):357–368. doi: 10.1007/s00109-012-0946-4

4. Coward JI, Kulbe H (2012) The role of interleukin-6 in gynaecological malignancies. Cytokine Growth Factor Rev 23(6):333–342. doi: 10.1016/j.cytogfr.2012.08.005

5. Coward J, Kulbe H, Chakravarty P, Leader D, Vassileva V, Leinster DA, Thompson R, Schioppa T, Nemeth J, Vermeulen J, Singh N, Avril N, Cummings J, Rexhepaj E, Jirstrom K, Gallagher WM, Brennan DJ, McNeish IA, Balkwill FR (2011) Interleukin-6 as a therapeutic target in human ovarian cancer. Clin Cancer Res 17(18):6083–6096. doi: 10.1158/1078-0432.CCR-11-0945

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