ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing
Author:
Funder
U.S. Department of Health & Human Services | National Institutes of Health
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
http://www.nature.com/articles/s41556-021-00709-7.pdf
Reference43 articles.
1. Jia, G. et al. N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat. Chem. Biol. 7, 885–887 (2011).
2. Zheng, G. et al. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol. Cell 49, 18–29 (2013).
3. Solberg, A. et al. Deletion of mouse Alkbh7 leads to obesity. J. Mol. Cell Biol. 5, 194–203 (2013).
4. Suzuki, T. et al. A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs. Nucleic Acids Res. 42, 7346–7357 (2014).
5. Barchiesi, A. et al. Transcription, processing, and decay of mitochondrial RNA in health and disease. Int. J. Mol. Sci. 20, 2221 (2019).
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