Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration-Reference-Cited by-同舟云学术

Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration

Published:2018-10-05 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Meliani Amine,Boisgerault Florence,Hardet Romain,Marmier Solenne,Collaud Fanny,Ronzitti Giuseppe,Leborgne Christian,Costa Verdera Helena,Simon Sola Marcelo,Charles Severine,Vignaud Alban,van Wittenberghe Laetitia,Manni Giorgia,Christophe Olivier,Fallarino Francesca^ORCID,Roy Christopher,Michaud Alicia,Ilyinskii Petr,Kishimoto Takashi Kei,Mingozzi Federico

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-06621-3.pdf

Reference60 articles.

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3. Manno, C. S. et al. Successful transduction of liver in hemophilia by AAV-factor IX and limitations imposed by the host immune response. Nat. Med. 12, 342–347 (2006).

4. Miesbach, W. et al. Gene therapy with adeno-associated virus vector 5-human factor IX in adults with hemophilia B. Blood 131, 1022–1031 (2018).

5. Nathwani, A. C. et al. Long-term safety and efficacy of factor IX gene therapy in hemophilia B. N. Engl. J. Med. 371, 1994–2004 (2014).

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