Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2-Reference-Cited by-同舟云学术

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2

Published:2019-03-13 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Caminero Alberto,McCarville Justin L.,Galipeau Heather J.,Deraison Celine,Bernier Steve P.,Constante Marco,Rolland Corinne,Meisel Marlies,Murray Joseph A.,Yu Xuechen B.^ORCID,Alaedini Armin,Coombes Brian K.,Bercik Premysl,Southward Carolyn M.,Ruf Wolfram^ORCID,Jabri Bana,Chirdo Fernando G.,Casqueiro Javier,Surette Michael G.,Vergnolle Nathalie^ORCID,Verdu Elena F.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-09037-9.pdf

Reference67 articles.

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2. Antalis, T. M., Shea-Donohue, T., Vogel, S. N., Sears, C. & Fasano, A. Mechanisms of disease: protease functions in intestinal mucosal pathobiology. Nat. Clin. Pract. Gastroenterol. Hepatol. 4, 393–402 (2007).

3. Cenac, N. et al. Role for protease activity in visceral pain in irritable bowel syndrome. J. Clin. Investig. 117, 636–647 (2007).

4. Gecse, K. et al. Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity. Gut 57, 591–599 (2008).

5. Bustos, D. et al. Colonic proteinases: increased activity in patients with ulcerative colitis. Medicina 58, 262–264 (1998).

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