Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
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Published:2018-06-11
Issue:1
Volume:9
Page:
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ISSN:2041-1723
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Container-title:Nature Communications
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language:en
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Short-container-title:Nat Commun
Author:
Dadaev TokhirORCID, , Saunders Edward J., Newcombe Paul J., Anokian Ezequiel, Leongamornlert Daniel A.ORCID, Brook Mark N.ORCID, Cieza-Borrella Clara, Mijuskovic Martina, Wakerell Sarah, Olama Ali Amin AlORCID, Schumacher Fredrick R.ORCID, Berndt Sonja I., Benlloch Sara, Ahmed Mahbubl, Goh Chee, Sheng Xin, Zhang Zhuo, Muir KennethORCID, Govindasami Koveela, Lophatananon Artitaya, Stevens Victoria L., Gapstur Susan M., Carter Brian D., Tangen Catherine M., Goodman Phyllis, Thompson Ian M., Batra JyotsnaORCID, Chambers Suzanne, Moya Leire, Clements Judith, Horvath Lisa, Tilley Wayne, Risbridger Gail, Gronberg Henrik, Aly Markus, Nordström TobiasORCID, Pharoah PaulORCID, Pashayan NoraORCID, Schleutker JohannaORCID, Tammela Teuvo L. J., Sipeky CsillaORCID, Auvinen Anssi, Albanes Demetrius, Weinstein Stephanie, Wolk AlicjaORCID, Hakansson Niclas, West Catharine, Dunning Alison M., Burnet Neil, Mucci Lorelei, Giovannucci Edward, Andriole Gerald, Cussenot Olivier, Cancel-Tassin GéraldineORCID, Koutros Stella, Freeman Laura E. Beane, Sorensen Karina DalsgaardORCID, Orntoft Torben Falck, Borre Michael, Maehle Lovise, Grindedal Eli Marie, Neal David E., Donovan Jenny L., Hamdy Freddie C., Martin Richard M., Travis Ruth C., Key Tim J., Hamilton Robert J., Fleshner Neil E., Finelli Antonio, Ingles Sue Ann, Stern Mariana C., Rosenstein Barry, Kerns SarahORCID, Ostrer HarryORCID, Lu Yong-Jie, Zhang Hong-Wei, Feng Ninghan, Mao Xueying, Guo Xin, Wang Guomin, Sun Zan, Giles Graham G., Southey Melissa C., MacInnis Robert J., FitzGerald Liesel M., Kibel Adam S., Drake Bettina F., Vega Ana, Gómez-Caamaño Antonio, Fachal LauraORCID, Szulkin Robert, Eklund Martin, Kogevinas ManolisORCID, Llorca Javier, Castaño-Vinyals Gemma, Penney Kathryn L., Stampfer Meir, Park Jong Y., Sellers Thomas A., Lin Hui-Yi, Stanford Janet L., Cybulski Cezary, Wokolorczyk Dominika, Lubinski Jan, Ostrander Elaine A., Geybels Milan S., Nordestgaard Børge G.ORCID, Nielsen Sune F., Weisher Maren, Bisbjerg Rasmus, Røder Martin Andreas, Iversen Peter, Brenner Hermann, Cuk Katarina, Holleczek Bernd, Maier Christiane, Luedeke Manuel, Schnoeller Thomas, Kim Jeri, Logothetis Christopher J., John Esther M., Teixeira Manuel R., Paulo Paula, Cardoso Marta, Neuhausen Susan L., Steele Linda, Ding Yuan Chun, De Ruyck Kim, De Meerleer Gert, Ost Piet, Razack Azad, Lim JasmineORCID, Teo Soo-Hwang, Lin Daniel W., Newcomb Lisa F., Lessel Davor, Gamulin Marija, Kulis Tomislav, Kaneva Radka, Usmani Nawaid, Slavov Chavdar, Mitev Vanio, Parliament Matthew, Singhal Sandeep, Claessens Frank, Joniau Steven, Van den Broeck Thomas, Larkin Samantha, Townsend Paul A., Aukim-Hastie Claire, Gago-Dominguez Manuela, Castelao Jose Esteban, Martinez Maria Elena, Roobol Monique J., Jenster Guido, van Schaik Ron H. N., Menegaux Florence, Truong ThérèseORCID, Koudou Yves Akoli, Xu JianfengORCID, Khaw Kay-Tee, Cannon-Albright Lisa, Pandha Hardev, Michael Agnieszka, Kierzek Andrzej, Thibodeau Stephen N., McDonnell Shannon K., Schaid Daniel J., Lindstrom Sara, Turman Constance, Ma Jing, Hunter David J., Riboli Elio, Siddiq Afshan, Canzian Federico, Kolonel Laurence N., Le Marchand Loic, Hoover Robert N., Machiela Mitchell J., Kraft Peter, Freedman Matthew, Wiklund Fredrik, Chanock Stephen, Henderson Brian E., Easton Douglas F.ORCID, Haiman Christopher A., Eeles Rosalind A.ORCID, Conti David V., Kote-Jarai Zsofia
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference71 articles.
1. Kote-Jarai, Z. et al. BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients. Br. J. Cancer 105, 1230–1234 (2011). 2. Pritchard, C. C. et al. Inherited DNA-repair gene mutations in men with metastatic prostate cancer. N. Engl. J. Med. 375, 443–453 (2016). 3. Mikropoulos, C., Goh, C., Leongamornlert, D., Kote-Jarai, Z. & Eeles, R. Translating genetic risk factors for prostate cancer to the clinic: 2013 and beyond. Future Oncol. 10, 1679–1694 (2014). 4. Conti, D. V. & Gauderman, W. J. SNPs, haplotypes, and model selection in a candidate gene region: the SIMPle analysis for multilocus data. Genet. Epidemiol. 27, 429–441 (2004). 5. Fridley, B. L. Bayesian variable and model selection methods for genetic association studies. Genet. Epidemiol. 33, 27–37 (2009).
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