Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism
Author:
Funder
Novo Nordisk
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-018-06219-9.pdf
Reference115 articles.
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2. Fuhrer, T., Zampieri, M., Sévin, D. C., Sauer, U. & Zamboni, N. Genomewide landscape of gene-metabolome associations in Escherichia coli. Mol. Syst. Biol. 13, 907 (2017).
3. Haverkorn van Rijsewijk, B. R. B., Nanchen, A., Nallet, S., Kleijn, R. J. & Sauer, U. Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli. Mol. Syst. Biol. 7, 477 (2011).
4. Long, C. P., Gonzalez, J. E., Sandoval, N. R. & Antoniewicz, M. R. Characterization of physiological responses to 22 gene knockouts in Escherichia coli central carbon metabolism. Metab. Eng. 37, 102–113 (2016).
5. Baba, T. et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2, 2006.0008 (2006).
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