A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-017-00154-x.pdf
Reference38 articles.
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3. Geerlings, A., Ibanez, M. M., Memelink, J., van Der Heijden, R. & Verpoorte, R. Molecular cloning and analysis of strictosidine beta-D-glucosidase, an enzyme in terpenoid indole alkaloid biosynthesis in Catharanthus roseus. J. Biol. Chem 275, 3051–3056 (2000).
4. Battersby, A. R. & Hall, E. S. Intermediacy of Geissoschizine in indole alkaloid biosynthesis. Rearrangement to the Strychnos skeleton. J. Chem. Soc. D, 793-794 (1969).
5. Scott, A. I., Cherry, P. C. & Qureshi, A. A. Mechanism of indole alkaloid biosynthesis. The Corynanthe-Strychnos relationship. J. Am. Chem. Soc. 91, 4932–4933 (1969).
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