A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate-Reference-Cited by-同舟云学术

A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate

Published:2017-08-22 Issue:1 Volume:8 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Tatsis Evangelos C.^ORCID,Carqueijeiro Inês^ORCID,Dugé de Bernonville Thomas^ORCID,Franke Jakob,Dang Thu-Thuy T.,Oudin Audrey,Lanoue Arnaud,Lafontaine Florent,Stavrinides Anna K.^ORCID,Clastre Marc,Courdavault Vincent^ORCID,O’Connor Sarah E.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-017-00154-x.pdf

Reference38 articles.

1. O’Connor, S. E. & Maresh, J. J. Chemistry and biology of monoterpene indole alkaloid biosynthesis. Nat. Prod. Rep. 23, 532–547 (2006).

2. Courdavault, V. et al. A look inside an alkaloid multisite plant: the Catharanthus logistics. Curr. Opin. Plant Biol. 19, 43–50 (2014).

3. Geerlings, A., Ibanez, M. M., Memelink, J., van Der Heijden, R. & Verpoorte, R. Molecular cloning and analysis of strictosidine beta-D-glucosidase, an enzyme in terpenoid indole alkaloid biosynthesis in Catharanthus roseus. J. Biol. Chem 275, 3051–3056 (2000).

4. Battersby, A. R. & Hall, E. S. Intermediacy of Geissoschizine in indole alkaloid biosynthesis. Rearrangement to the Strychnos skeleton. J. Chem. Soc. D, 793-794 (1969).

5. Scott, A. I., Cherry, P. C. & Qureshi, A. A. Mechanism of indole alkaloid biosynthesis. The Corynanthe-Strychnos relationship. J. Am. Chem. Soc. 91, 4932–4933 (1969).

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