A de novo synthesis of the bisindole alkaloid geissolosimine: collective synthesis of geissoschizoline, akuammicine, (16S)-deshydroxymethylstemmadenine and Aspidospermatan alkaloids-Reference-Cited by-同舟云学术

A de novo synthesis of the bisindole alkaloid geissolosimine: collective synthesis of geissoschizoline, akuammicine, (16S)-deshydroxymethylstemmadenine and Aspidospermatan alkaloids

Published:2024 Issue:3 Volume:11 Page:703-708
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Yan Jiahang¹,Zhen Yanxia¹,Wang Pengyan¹,Han Yimeng¹,Zou Huanhuan¹,Chen Junhan¹,He Weigang²,Xie Weiqing¹³^ORCID

Affiliation:

1. Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, 22 Xinong Road, Yangling, 712100, Shaanxi, China

2. School of Biology and Food Engineering, Changshu Institute of Technology, Changshu, 215500, Jiangsu, China

3. Key Laboratory of Botanical Pesticide R&D in Shaanxi Province, Yangling, 712100, Shaanxi, China

Abstract

Collective synthesis of geissolosimine, geissoschizoline, akuammicine, (16S)-deshydroxymethylstemmadenine and Aspidospermatan alkaloids was achieved based on a catalytic asymmetric double Michael addition.

Funder

National Basic Research Program of China

Northwest A and F University

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D3QO01898A

Reference40 articles.

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3. Sur la geissospermine

4. La 12′-hydroxyisostrychnobiline: Nouvel alcaloïde du Strychnos variabilis

5. Characterization of alkaloids in bark extracts of Geissospermum vellosii by HPLC-UV-diode array-multistage high-resolution mass spectrometry

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