Engineered and natural gene drives: mechanistically the same, yet not same in kind
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry,Multidisciplinary
Link
https://www.nature.com/articles/s41467-023-41727-3.pdf
Reference12 articles.
1. James, S. L., O’brochta, D. A., Randazzo, F. & Akbari, O. S. A gene drive is a gene drive: the debate over lumping or splitting definitions. Nat. Commun. 14, 1749 (2023).
2. Esvelt, K. M., Smidler, A. L., Catteruccia, F. & Church, G. M. Concerning RNA-guided gene drives for the alteration of wild populations. Elife 3. https://doi.org/10.7554/eLife.03401 (2014).
3. Brossard, D., Belluck, P., Gould, F. & Wirz, C. D. Promises and perils of gene drives: navigating the communication of complex, post-normal science. Proc. Natl Acad. Sci. USA 116, 7692–7697 (2019).
4. Vergara, M. M., Labbé, J. & Tannous, J. Reflection on the challenges, accomplishments, and new Frontiers of Gene Drives. BioDesign Res. 2022, 9853416 (2022).
5. Wells, M. A. & Steinbrecher, R. A. Natural selfish genetic elements should not be defined as gene drives. Proc. Natl Acad. Sci. USA 119, e2201142119 (2022).
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