SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden

Author:

Rudberg Ann-SofieORCID,Havervall Sebastian,Månberg AnnaORCID,Jernbom Falk AugustORCID,Aguilera Katherina,Ng HenryORCID,Gabrielsson Lena,Salomonsson Ann-Christin,Hanke LeoORCID,Murrell Ben,McInerney GeraldORCID,Olofsson Jennie,Andersson EniORCID,Hellström CeciliaORCID,Bayati Shaghayegh,Bergström Sofia,Pin Elisa,Sjöberg Ronald,Tegel Hanna,Hedhammar My,Phillipson Mia,Nilsson PeterORCID,Hober SophiaORCID,Thålin CharlotteORCID

Abstract

AbstractSARS-CoV-2 may pose an occupational health risk to healthcare workers. Here, we report the seroprevalence of SARS-CoV-2 antibodies, self-reported symptoms and occupational exposure to SARS-CoV-2 among healthcare workers at a large acute care hospital in Sweden. The seroprevalence of IgG antibodies against SARS-CoV-2 was 19.1% among the 2149 healthcare workers recruited between April 14th and May 8th 2020, which was higher than the reported regional seroprevalence during the same time period. Symptoms associated with seroprevalence were anosmia (odds ratio (OR) 28.4, 95% CI 20.6–39.5) and ageusia (OR 19.2, 95% CI 14.3–26.1). Seroprevalence was also associated with patient contact (OR 2.9, 95% CI 1.9–4.5) and covid-19 patient contact (OR 3.3, 95% CI 2.2–5.3). These findings imply an occupational risk for SARS-CoV-2 infection among healthcare workers. Continued measures are warranted to assure healthcare workers safety and reduce transmission from healthcare workers to patients and to the community.

Funder

Familjen Erling-Perssons Stiftelse

Science for Life Laboratory

Vetenskapsrådet

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

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