Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer-Reference-Cited by-同舟云学术

Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer

Published:2018-10-23 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Schneider Jeffrey A.,Craven Timothy W.,Kasper Amanda C.,Yun Chi,Haugbro Michael,Briggs Erica M.,Svetlov Vladimir,Nudler Evgeny,Knaut Holger,Bonneau Richard,Garabedian Michael J.,Kirshenbaum Kent,Logan Susan K.

Funder

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-06845-3.pdf

Reference72 articles.

1. Wojcik, P. & Berlicki, L. Peptide-based inhibitors of protein–protein interactions. Bioorg. Med. Chem. Lett. 26, 707–713 (2016).

2. Arkin, M. R., Tang, Y. & Wells, J. A. Small-molecule inhibitors of protein–protein interactions: progressing toward the reality. Chem. Biol. 21, 1102–1114 (2014).

3. Ran, X. & Gestwicki, J. E. Inhibitors of protein–protein interactions (PPIs): an analysis of scaffold choices and buried surface area. Curr. Opin. Chem. Biol. 44, 75–86 (2018).

4. Rubin, S. & Qvit, N. Cyclic peptides for protein–protein interaction targets: applications to human disease. Crit. Rev. Eukaryot. Gene Expr. 26, 199–221 (2016).

5. Matsson, P. & Kihlberg, J. How big is too big for cell permeability? J. Med. Chem. 60, 1662–1664 (2017).

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