Plk1 overexpression induces chromosomal instability and suppresses tumor development-Reference-Cited by-同舟云学术

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Plk1 overexpression induces chromosomal instability and suppresses tumor development

Published:2018-08-01 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

de Cárcer Guillermo^ORCID,Venkateswaran Sharavan Vishaan^ORCID,Salgueiro Lorena,El Bakkali Aicha,Somogyi Kalman,Rowald Konstantina,Montañés Pablo^ORCID,Sanclemente Manuel,Escobar Beatriz,de Martino Alba^ORCID,McGranahan Nicholas,Malumbres Marcos^ORCID,Sotillo Rocío^ORCID

Funder

EC | Seventh Framework Programme (European Union Seventh Framework Programme)

EC | European Research Council (ERC)

Howard Hughes Medical Institute (HHMI)

Worldwide Cancer Research

Consejería de Sanidad, Comunidad de Madrid

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-05429-5.pdf

Reference70 articles.

1. Holland, A. J. & Cleveland, D. W. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat. Rev. Mol. Cell Biol. 10, 478–487 (2009).

2. Schvartzman, J. M., Sotillo, R. & Benezra, R. Mitotic chromosomal instability and cancer: mouse modelling of the human disease. Nat. Rev. Cancer 10, 102–115 (2010).

3. Weaver, B. A., Silk, A. D., Montagna, C., Verdier-Pinard, P. & Cleveland, D. W. Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell 11, 25–36 (2007).

4. Santaguida, S. & Amon, A. Short- and long-term effects of chromosome mis-segregation and aneuploidy. Nat. Rev. Mol. Cell Biol. 16, 473–485 (2015).

5. Rowald, K. et al. Negative selection and chromosome instability induced by Mad2 overexpression delay breast cancer but facilitate oncogene-independent outgrowth. Cell Rep. 15, 2679–2691 (2016).

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