Global genetic diversity, introgression, and evolutionary adaptation of indicine cattle revealed by whole genome sequencing

Author:

Chen NingboORCID,Xia Xiaoting,Hanif QuratulainORCID,Zhang Fengwei,Dang Ruihua,Huang Bizhi,Lyu Yang,Luo Xiaoyu,Zhang Hucai,Yan Huixuan,Wang Shikang,Wang Fuwen,Chen Jialei,Guan Xiwen,Liu Yangkai,Li Shuang,Jin LiangliangORCID,Wang Pengfei,Sun Luyang,Zhang Jicai,Liu Jianyong,Qu Kaixing,Cao Yanhong,Sun Junli,Liao Yuying,Xiao Zhengzhong,Cai MingORCID,Mu Lan,Siddiki Amam Zonaed,Asif Muhammad,Mansoor Shahid,Babar Masroor Ellahi,Hussain TanveerORCID,Silva Gamamada Liyanage Lalanie Pradeepa,Gorkhali Neena Amatya,Terefe EndashawORCID,Belay Gurja,Tijjani Abdulfatai,Zegeye TsadkanORCID,Gebre Mebrate Genet,Ma Yun,Wang Yu,Huang Yongzhen,Lan Xianyong,Chen Hong,Migliore Nicola RambaldiORCID,Colombo GiuliaORCID,Semino OrnellaORCID,Achilli AlessandroORCID,Sinding Mikkel-Holger S.ORCID,Lenstra Johannes A.ORCID,Cheng Haijian,Lu Wenfa,Hanotte OlivierORCID,Han JianlinORCID,Jiang YuORCID,Lei ChuzhaoORCID

Abstract

AbstractIndicine cattle, also referred to as zebu (Bos taurus indicus), play a central role in pastoral communities across a wide range of agro-ecosystems, from extremely hot semiarid regions to hot humid tropical regions. However, their adaptive genetic changes following their dispersal into East Asia from the Indian subcontinent have remained poorly documented. Here, we characterize their global genetic diversity using high-quality whole-genome sequencing data from 354 indicine cattle of 57 breeds/populations, including major indicine phylogeographic groups worldwide. We reveal their probable migration into East Asia was along a coastal route rather than inland routes and we detected introgression from other bovine species. Genomic regions carrying morphology-, immune-, and heat-tolerance-related genes underwent divergent selection according to Asian agro-ecologies. We identify distinct sets of loci that contain promising candidate variants for adaptation to hot semi-arid and hot humid tropical ecosystems. Our results indicate that the rapid and successful adaptation of East Asian indicine cattle to hot humid environments was promoted by localized introgression from banteng and/or gaur. Our findings provide insights into the history and environmental adaptation of indicine cattle.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry,Multidisciplinary

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3