Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-017-02295-5.pdf
Reference23 articles.
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2. Gay, L., Baker, A. M. & Graham, T. A. Tumour Cell Heterogeneity. F1000Res 5, (F1000 Faculty Rev): 238 (2016).
3. Yates, L. R. et al. Subclonal diversification of primary breast cancer revealed by multiregion sequencing. Nat. Med. 21, 751–759 (2015).
4. Wang, Y. et al. Clonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature 512, 155–160 (2014).
5. Wang, F. et al. RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues. J. Mol. Diagn. 14, 22–29 (2012).
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