RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia-Reference-Cited by-同舟云学术

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RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia

Published:2004-07-04 Issue:8 Volume:10 Page:816-820
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Xia Haibin,Mao Qinwen,Eliason Steven L,Harper Scott Q,Martins Inês H,Orr Harry T,Paulson Henry L,Yang Linda,Kotin Robert M,Davidson Beverly L

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm1076.pdf

Reference25 articles.

1. Orr, H.T. et al. Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1. Nat. Genet. 4, 221–226 (1993).

2. Zoghbi, H.Y. & Orr, H.T. Spinocerebellar ataxia type 1. Semin. Cell Biol. 6, 29–35 (1995).

3. Skinner, P.J. et al. Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures. Nature 389, 971–234 (1997).

4. Fernandez-Funez, P. et al. Identification of genes that modify ataxin-1-induced neurodegeneration. Nature 408, 101–106 (2000).

5. Burright, E.N. et al. SCA1 transgenic mice: a model for neurodegeneration caused by an expanded CAG trinucleotide repeat. Cell 82, 937–948 (1995).

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