An autologous antigen-agnostic dendritic cell therapy that forgoes antigen loading
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
https://www.nature.com/articles/s43018-023-00674-0.pdf
Reference5 articles.
1. Perez, C. R. & De Palma, M. Engineering dendritic cell vaccines to improve cancer immunotherapy. Nat. Commun. 10, 5408 (2019). A review article that illustrates DC-engineering strategies, with a focus on cDC1s.
2. Cabeza-Cabrerizo, M., Cardoso, A., Minutti, C. M., Pereira da Costa, M. & Reis e Sousa, C. Dendritic cells revisited. Annu. Rev. Immunol. 39, 131–166 (2021). A review article that discusses DC biology.
3. Harari, A., Graciotti, M., Bassani-Sternberg, M. & Kandalaft, L. E. Antitumour dendritic cell vaccination in a priming and boosting approach. Nat. Rev. Drug Discov. 19, 635–652 (2020). A review article that discusses clinical applications of DC-based therapies.
4. Lerner, E. C. et al. CD8+ T cells maintain killing of MHC-I-negative tumor cells through the NKG2D‒NKG2DL axis. Nat. Cancer 4, 1258–1272 (2023). A research article that describes antigen-independent tumor rejection by T cells.
5. Squadrito, M. L., Cianciaruso, C., Hansen, S. K. & De Palma, M. EVIR: chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens. Nat. Methods 15, 183–186 (2018). A research article that introduces a chimeric receptor that promotes antigen acquisition by DCs.
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