KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming
-
Published:2022-04-21
Issue:6
Volume:3
Page:753-767
-
ISSN:2662-1347
-
Container-title:Nature Cancer
-
language:en
-
Short-container-title:Nat Cancer
Author:
Na Feifei, Pan Xiangyu, Chen Jingyao, Chen Xuelan, Wang Manli, Chi Pengliang, You Liting, Zhang Lanxin, Zhong Ailing, Zhao Lei, Dai Siqi, Zhang Mengsha, Wang Yiyun, Wang Bo, Zheng Jianan, Wang Yuying, Xu Jing, Wang Jian, Wu Baohong, Chen Mei, Liu Hongyu, Xue Jianxin, Huang Meijuan, Gong Youling, Zhu Jiang, Zhou Lin, Zhang Yan, Yu Min, Tian Panwen, Fan Mingyu, Lu Zhenghao, Xue Zhihong, Zhao Yinglan, Yang Hanshuo, Zhao Chengjian, Wang YuanORCID, Han JunhongORCID, Yang Shengyong, Xie DanORCID, Chen LuORCID, Zhong QianORCID, Zeng Musheng, Lowe Scott W.ORCID, Lu YouORCID, Liu YuORCID, Wei Yuquan, Chen ChongORCID
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Reference48 articles.
1. Valastyan, S. & Weinberg, R. A. Tumor metastasis: molecular insights and evolving paradigms. Cell 147, 275–292 (2011). 2. Hu, Z., Li, Z., Ma, Z. & Curtis, C. Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases. Nat. Genet. 52, 701–708 (2020). 3. Reiter, J. G. et al. Minimal functional driver gene heterogeneity among untreated metastases. Science 361, 1033–1037 (2018). 4. Makohon-Moore, A. P. et al. Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer. Nat. Genet. 49, 358–366 (2017). 5. Ramaswamy, S., Ross, K. N., Lander, E. S. & Golub, T. R. A molecular signature of metastasis in primary solid tumors. Nat. Genet. 33, 49–54 (2003).
Cited by
56 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|