Relatedness in the post-genomic era: is it still useful?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg3821.pdf
Reference93 articles.
1. Grafen, A. A geometric view of relatedness. Oxford Surv. Evol. Biol. 2, 28–90 (1985).
2. Maynard Smith, J. Evolutionary Genetics (Oxford Univ. Press, 1998).
3. Rousset, F. Inbreeding and relatedness coefficients: what do they measure? Heredity 88, 371–380 (2002). This paper gives a critical examination of kinship coefficients and proposes a new approach to measure kinship based on a cumulative excess of recent coalescences.
4. Powell, J., Visscher, P. & Goddard, M. Reconciling the analysis of IBD and IBS in complex trait studies. Nature Rev. Genet. 11, 800–805 (2010). This is a review on IBS and IBD concepts, with a focus on choice of reference population; it also discusses SNP-based computation of relatedness coefficients and their use in heritability estimation.
5. Weir, B., Anderson, A. & Hepler, A. Genetic relatedness analysis: modern data and new challenges. Nature Rev. Genet. 7, 771–780 (2006).
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