Novel targets for Huntington's disease in an mTOR-independent autophagy pathway-Reference-Cited by-同舟云学术

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

Published:2008-03-23 Issue:5 Volume:4 Page:295-305
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Williams Andrea,Sarkar Sovan,Cuddon Paul,Ttofi Evangelia K,Saiki Shinji,Siddiqi Farah H,Jahreiss Luca,Fleming Angeleen,Pask Dean,Goldsmith Paul,O'Kane Cahir J,Floto Rodrigo Andres,Rubinsztein David C

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.79.pdf

Reference50 articles.

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2. Klionsky, D.J. & Emr, S.D. Autophagy as a regulated pathway of cellular degradation. Science 290, 1717–1721 (2000).

3. Rubinsztein, D.C. Lessons from animal models of Huntington's disease. Trends Genet. 18, 202–209 (2002).

4. Gafni, J. & Ellerby, L.M. Calpain activation in Huntington's disease. J. Neurosci. 22, 4842–4849 (2002).

5. Gafni, J. et al. Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus. J. Biol. Chem. 279, 20211–20220 (2004).

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