Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation-Reference-Cited by-同舟云学术

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Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation

Published:2012-02-26 Issue:4 Volume:8 Page:393-399
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Yuzwa Scott A,Shan Xiaoyang,Macauley Matthew S,Clark Thomas,Skorobogatko Yuliya,Vosseller Keith,Vocadlo David J

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.797.pdf

Reference50 articles.

1. Bierer, L.M. et al. Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease. Arch. Neurol. 52, 81–88 (1995).

2. Hutton, M. et al. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 393, 702–705 (1998).

3. Goedert, M., Jakes, R. & Crowther, R.A. Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments. FEBS Lett. 450, 306–311 (1999).

4. Vogelsberg-Ragaglia, V. et al. Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells. Mol. Biol. Cell 11, 4093–4104 (2000).

5. Lewis, J. et al. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet. 25, 402–405 (2000).

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