Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles-Reference-Cited by-同舟云学术

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

Published:2012-04-01 Issue:5 Volume:8 Page:471-476
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Serafimova Iana M,Pufall Miles A,Krishnan Shyam,Duda Katarzyna,Cohen Michael S,Maglathlin Rebecca L,McFarland Jesse M,Miller Rand M,Frödin Morten,Taunton Jack

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.925.pdf

Reference28 articles.

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4. Singh, J., Petter, R.C., Baillie, T.A. & Whitty, A. The resurgence of covalent drugs. Nat. Rev. Drug Discov. 10, 307–317 (2011).

5. Fry, D.W. et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc. Natl. Acad. Sci. USA 95, 12022–12027 (1998).

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