Ligand-binding dynamics rewire cellular signaling via estrogen receptor-α-Reference-Cited by-同舟云学术

Ligand-binding dynamics rewire cellular signaling via estrogen receptor-α

Published:2013-03-24 Issue:5 Volume:9 Page:326-332
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Srinivasan Sathish,Nwachukwu Jerome C,Parent Alex A,Cavett Valerie,Nowak Jason,Hughes Travis S,Kojetin Douglas J,Katzenellenbogen John A,Nettles Kendall W

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.1214.pdf

Reference50 articles.

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2. Carroll, M.J. et al. Evidence for dynamics in proteins as a mechanism for ligand dissociation. Nat. Chem. Biol. 8, 246–252 (2012).

3. Shiau, A.K. et al. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 95, 927–937 (1998).

4. Nettles, K.W. et al. CBP Is a dosage-dependent regulator of nuclear factor-κB suppression by the estrogen receptor. Mol. Endocrinol. 22, 263–272 (2008).

5. Bruning, J.B. et al. Coupling of receptor conformation and ligand orientation determine graded activity. Nat. Chem. Biol. 6, 837–843 (2010).

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