Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target-Reference-Cited by-同舟云学术

Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target

Published:2011-07-17 Issue:9 Volume:7 Page:610-616
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Chen Ting,Ozel Duygu,Qiao Yuan,Harbinski Fred,Chen Limo,Denoyelle Séverine,He Xiaoying,Zvereva Nela,Supko Jeffrey G,Chorev Michael,Halperin Jose A,Aktas Bertal H

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.613.pdf

Reference42 articles.

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3. Harding, H.P. et al. Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development. Proc. Natl. Acad. Sci. USA 106, 1832–1837 (2009).

4. Heaney, J.D., Michelson, M.V., Youngren, K.K., Lam, M.Y. & Nadeau, J.H. Deletion of eIF2beta suppresses testicular cancer incidence and causes recessive lethality in agouti-yellow mice. Hum. Mol. Genet. 18, 1395–1404 (2009).

5. Skalnikova, H. et al. Protein signaling pathways in differentiation of neural stem cells. Proteomics 8, 4547–4559 (2008).

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