Small-molecule factor D inhibitors targeting the alternative complement pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nchembio.2208.pdf
Reference50 articles.
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2. Ricklin, D., Hajishengallis, G., Yang, K. & Lambris, J.D. Complement: a key system for immune surveillance and homeostasis. Nat. Immunol. 11, 785–797 (2010).
3. Thurman, J.M. & Holers, V.M. The central role of the alternative complement pathway in human disease. J. Immunol. 176, 1305–1310 (2006).
4. Holers, V.M. The spectrum of complement alternative pathway-mediated diseases. Immunol. Rev. 223, 300–316 (2008).
5. Risitano, A.M. Paroxysmal nocturnal hemoglobinuria and the complement system: recent insights and novel anticomplement strategies. Adv. Exp. Med. Biol. 735, 155–172 (2013).
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