Directed evolution of hydrolases for prevention of G-type nerve agent intoxication-Reference-Cited by-同舟云学术

Directed evolution of hydrolases for prevention of G-type nerve agent intoxication

Published:2011-01-09 Issue:2 Volume:7 Page:120-125
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Gupta Rinkoo D,Goldsmith Moshe,Ashani Yacov,Simo Yair,Mullokandov Gavriel,Bar Hagit,Ben-David Moshe,Leader Haim,Margalit Raanan,Silman Israel,Sussman Joel L,Tawfik Dan S

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.510.pdf

Reference28 articles.

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2. Lenz, D.E. et al. Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: a mini review. Toxicology 233, 31–39 (2007).

3. Ashani, Y. & Pistinner, S. Estimation of the upper limit of human butyrylcholinesterase dose required for protection against organophosphates toxicity: a mathematically based toxicokinetic model. Toxicol. Sci. 77, 358–367 (2004).

4. diTargiani, R.C., Chandrasekaran, L., Belinskaya, T. & Saxena, A. In search of a catalytic bioscavenger for the prophylaxis of nerve agent toxicity. Chem. Biol. Interact. 187, 349–354 (2010).

5. Ghanem, E. & Raushel, F.M. Detoxification of organophosphate nerve agents by bacterial phosphotriesterase. Toxicol. Appl. Pharmacol. 207, 459–470 (2005).

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