Multienzyme docking in hybrid megasynthetases
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nchembio.2007.61.pdf
Reference47 articles.
1. Weissman, K.J. & Leadlay, P.F. Combinatorial biosynthesis of reduced polyketides. Nat. Rev. Microbiol. 3, 925–936 (2005).
2. Grunewald, J. & Marahiel, M.A. Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptides. Microbiol. Mol. Biol. Rev. 70, 121–146 (2006).
3. Fischbach, M.A. & Walsh, C.T. Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: logic, machinery and mechanisms. Chem. Rev. 106, 3468–3496 (2006).
4. Müller, R. Don't classify polyketide synthases. Chem. Biol. 11, 4–6 (2004).
5. Gokhale, R.S., Tsuji, S.Y., Cane, D.E. & Khosla, C. Dissecting and exploiting intermodular communication in polyketide synthases. Science 284, 482–485 (1999).
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