Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd2945.pdf
Reference250 articles.
1. Walgren, J. L. & Thompson, D. C. Application of proteomic technologies in the drug development process. Toxicol. Lett. 149, 377–385 (2004).
2. Sleno, L. & Emili, A. Proteomic methods for drug target discovery. Curr. Opin. Chem. Biol. 12, 46–54 (2008).
3. Stelzl, U. et al. A human protein-protein interaction network: a resource for annotating the proteome. Cell 122, 957–968 (2005).
4. Ideker, T., Galitski, T. & Hood, L. A new approach to decoding life: systems biology. Annu. Rev. Genomics Hum. Genet. 2, 343–372 (2001).
5. Butler, G. S., Dean, R. A., Tam, E. & Overall, C. M. Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of matrix metalloproteinase-14 (MT1-MMP) mediated membrane protein shedding. Mol. Cell Biol. 28, 4896–4914 (2008).
Cited by 121 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. An Artificial Intelligence-Based Stacked Ensemble Approach for Prediction of Protein Subcellular Localization in Confocal Microscopy Images;Sustainability;2023-01-16
2. High-precision, low-complexity, high-resolution microscopy-based cell sorting;Lab on a Chip;2023
3. Grouper TRIM23 exerts antiviral activity against iridovirus and nodavirus;Frontiers in Immunology;2022-09-20
4. Circulating SOD2 Is a Candidate Response Biomarker for Neoadjuvant Therapy in Breast Cancer;Cancers;2022-08-10
5. Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy;Nature Communications;2022-05-23
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3