Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/nm.4055.pdf
Reference30 articles.
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2. Koboldt, D.C. et al. Comprehensive molecular portraits of human breast tumors. Nature 490, 61–70 (2012).
3. Hu, S. et al. [13C]pyruvate imaging reveals alterations in glycolysis that precede c-Myc–induced tumor formation and regression. Cell Metab. 14, 131–142 (2011).
4. Wahlström, T. & Henriksson, M.A. Impact of MYC in regulation of tumor cell metabolism. Biochim. Biophys. Acta 1849, 563–569 (2015).
5. D'Cruz, C.M. et al. c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat. Med. 7, 235–239 (2001).
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