c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations

Author:

D'Cruz Celina M.,Gunther Edward J.,Boxer Robert B.,Hartman Jennifer L.,Sintasath Louis,Moody Susan E.,Cox James D.,Ha Seung I.,Belka George K.,Golant Alexander,Cardiff Robert D.,Chodosh Lewis A.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference24 articles.

1. Guerin, M., Barrois, M., Terrier, M.J., Spielmann, M. & Riou, G. Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: correlation with poor prognosis. Oncogene Res. 3, 21–31 (1988).

2. Varley, J.M., Swallow, J.E., Brammar, W.J., Whittaker, J.L. & Walker, R.A. Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis. Oncogene 1, 423–430 (1987).

3. Gossen, M. et al. Transcriptional activation by tetracyclines in mammalian cells. Science 268, 1766–1769 (1995).

4. Murphy, W. et al. A translocated human c-myc oncogene is altered in a conserved coding sequence. Proc. Natl. Acad. Sci. USA 83, 2939–2943 (1986).

5. Marhin, W.W., Chen, S., Facchini, L.M., Fornace, A.J., Jr. & Penn, L.Z. Myc represses the growth arrest gene gadd45. Oncogene 14, 2825–2834 (1997).

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