TCR sequencing paired with massively parallel 3′ RNA-seq reveals clonotypic T cell signatures-Reference-Cited by-同舟云学术

TCR sequencing paired with massively parallel 3′ RNA-seq reveals clonotypic T cell signatures

Published:2019-11-19 Issue:12 Volume:20 Page:1692-1699
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Tu Ang A.^ORCID,Gierahn Todd M.,Monian Brinda,Morgan Duncan M.^ORCID,Mehta Naveen K.,Ruiter Bert,Shreffler Wayne G.,Shalek Alex K.^ORCID,Love J. Christopher^ORCID

Funder

Broad Institute

U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases

Koch Institute - Dana-Farber/Harvard Cancer Center Bridge Project.

U.S. Department of Health & Human Services | National Institutes of Health

Searle Scholars Program, Beckman Young Investigator Program,Pew-Stewart Scholars Program for Cancer Research

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/s41590-019-0544-5.pdf

Reference53 articles.

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2. Lossius, A. et al. High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+ T cells. Eur. J. Immunol. 44, 1–41 (2014).

3. Kirsch, I. R. et al. TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL. Sci. Transl. Med. 7, 1–13 (2015).

4. Carlson, C. S. et al. Using synthetic templates to design an unbiased multiplex PCR assay. Nat. Commun. 4, 2680 (2013).

5. Crosby, E. J. et al. Complimentary mechanisms of dual checkpoint blockade expand unique T-cell repertoires and activate adaptive anti-tumor immunity in triple-negative breast tumors. Oncoimmunology 7, e1421891 (2018).

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