TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL-Reference-Cited by-同舟云学术

TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL

Published:2015-10-07 Issue:308 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Kirsch Ilan R.¹,Watanabe Rei²,O’Malley John T.²,Williamson David W.¹,Scott Laura-Louise²,Elco Christopher P.³,Teague Jessica E.²,Gehad Ahmed²,Lowry Elizabeth L.²,LeBoeuf Nicole R.²⁴,Krueger James G.⁵,Robins Harlan S.¹,Kupper Thomas S.²⁴,Clark Rachael A.²⁴

Affiliation:

1. Adaptive Biotechnologies, Seattle, WA 98102, USA.

2. Department of Dermatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

3. Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

4. Dana-Farber/Brigham and Women’s Cancer Center, Boston, MA 02115, USA.

5. Department of Dermatology, Rockefeller University, New York, NY 10065, USA.

Abstract

High-throughput TCR sequencing can accurately diagnose and discriminate CTCL cells in skin.

Funder

NIH/NCI (National Cancer Institute)

NIAID (National Institute of Allergy and Infectious Diseases)

NIH/NIAMS (National Institute of Arthritis and Musculoskeletal and Skin Diseases)

NIH/NIAMS

Leukemia and Lymphoma Society

Damon Runyon Clinical Investigator Award

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference42 articles.

1. WHO-EORTC classification for cutaneous lymphomas

2. Long-term Outcome of 525 Patients With Mycosis Fungoides and Sézary Syndrome

3. NCCN Guidelines ® (National Comprehensive Cancer Network Inc. Fort Washington PA 2009); www.NCCN.org.

4. Localization of clonal T cells to the epidermis in cutaneous T-cell lymphoma

5. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936

Cited by 178 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cutaneous T-cell Lymphoma;Hematology/Oncology Clinics of North America;2024-10

2. Human TCR repertoire in cancer;Cancer Medicine;2024-09

3. The skin microbiome stratifies patients with cutaneous T cell lymphoma and determines event-free survival;npj Biofilms and Microbiomes;2024-08-29

4. Assessing T‐cell receptor clonality by next‐generation sequencing in atypical cutaneous lymphoid infiltrates and cutaneous T‐cell lymphoma: A scoping review;Journal of Cutaneous Pathology;2024-07-18

5. Histopathologic and Clinical Characterization of Brentuximab Vedotin-associated Rash;American Journal of Surgical Pathology;2024-06-20