APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints

Author:

Yin Zhuoran,Rosenzweig Neta,Kleemann Kilian L.,Zhang Xiaoming,Brandão Wesley,Margeta Milica A.,Schroeder Caitlin,Sivanathan Kisha N.,Silveira Sebastian,Gauthier Christian,Mallah Dania,Pitts Kristen M.ORCID,Durao Ana,Herron Shawn,Shorey Hannah,Cheng Yiran,Barry Jen-Li,Krishnan Rajesh K.,Wakelin Sam,Rhee Jared,Yung AnthonyORCID,Aronchik Michael,Wang Chao,Jain Nimansha,Bao Xin,Gerrits Emma,Brouwer Nieske,Deik AmyORCID,Tenen Daniel G.ORCID,Ikezu TsuneyaORCID,Santander Nicolas G.ORCID,McKinsey Gabriel L.,Baufeld Caroline,Sheppard DeanORCID,Krasemann SusanneORCID,Nowarski Roni,Eggen Bart J. L.ORCID,Clish ClaryORCID,Tanzi Rudolph E.ORCID,Madore Charlotte,Arnold Thomas D.,Holtzman David M.,Butovsky OlegORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute on Aging

U.S. Department of Health & Human Services | NIH | National Eye Institute

U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke

BrightFocus Foundation

Cure Alzheimer’s Fund

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

Nancy Davis Foundation for Multiple Sclerosis

Alzheimer’s Association

National Multiple Sclerosis Society

U.S. Department of Defense

Research to Prevent Blindness

Glaucoma Research Foundation

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

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