Thymic regulatory T cells arise via two distinct developmental programs-Reference-Cited by-同舟云学术

Thymic regulatory T cells arise via two distinct developmental programs

Published:2019-01-14 Issue:2 Volume:20 Page:195-205
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Owen David L.,Mahmud Shawn A.,Sjaastad Louisa E.,Williams Jason B.,Spanier Justin A.,Simeonov Dimitre R.^ORCID,Ruscher Roland,Huang Weishan^ORCID,Proekt Irina^ORCID,Miller Corey N.^ORCID,Hekim Can,Jeschke Jonathan C.,Aggarwal Praful,Broeckel Ulrich,LaRue Rebecca S.,Henzler Christine M.,Alegre Maria-Luisa,Anderson Mark S.,August Avery^ORCID,Marson Alexander,Zheng Ye^ORCID,Williams Calvin B.,Farrar Michael A.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/s41590-018-0289-6.pdf

Reference56 articles.

1. Lio, C. W. & Hsieh, C. S. A two-step process for thymic regulatory T cell development. Immunity 28, 100–111 (2008).

2. Burchill, M. A. et al. Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire. Immunity 28, 112–121 (2008).

3. Mahmud, S. A. et al. Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells. Nat. Immunol. 15, 473–481 (2014).

4. Burchill, M. A., Yang, J., Vogtenhuber, C., Blazar, B. R. & Farrar, M. A. IL-2 receptor β-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells. J. Immunol. 178, 280–290 (2007).

5. Yao, Z. et al. Nonredundant roles for Stat5a/b in directly regulating Foxp3. Blood 109, 4368–4375 (2007).

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